"Face to Face" also won Jury Awards for Best Actor (Vince Colosimo), Best Actress (Ra Chapman) and Best Director (Michael Rymer).
More than 2,000 films were reviewed and more than 400 picked by the selection committee to be a part of the 2011 festival.
Officials estimated that more than 50,000 people attended the festival from April 28 to Thursday.
The 2011 MacGillivray Freeman Films Awards, a new recognition for documentary filmmaking, was awarded to three films.
"My So-Called Enemy" was awarded for Excellence in Documentary Filmmaking in the feature category and "The Dancer" received the same award in the short films category.
"This is Your Ocean: Sharks" also received the MacGillivray Freeman Films Special Achievement Award in Environmental Filmmaking.
2011 Newport Beach Film Festival award winners
Best Feature Film: "A Beginner's Guide to Endings"
Best Actor: Vince Colosimo, "Face to Face"
Best Actress: Ra Chapman, "Face to Face"
Best Director: Michael Rymer, "Face to Face"
Best Cinematographer: Samy Inayeh, "A Beginner's Guide to Endings"
Best Screenplay: Jonathan Sobol, "A Beginner's Guide to Endings"
Best Feature Documentary Film: "My So-Called Enemy," director Lisa Gossels
Honorable Mention: "We Were Here," directors David Weissman, Bill Weber
Best Short Documentary FILM: "Warriors of Qiugang," director Ruby Yang
Honorable Mention: "Moth in Spring," director Yu Gu
Best Short Animated Film: "Fly," director Alan Short
Honorable Mention: "Bottle," director Kirsten Lepore
Best Narrative Short Film: "Love Song of Iskra Prufrock," director Lucy Gaffy
Honorable Mention: "The Escape," director James Connelly
2011 Audience Awards