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New treatment found for skeletal muscle disorder

March 25, 2008

UCI scientists have discovered a new treatment for the most common skeletal muscle disorder for people 50 and older, officials said.

A new study shows that lithium chloride, normally used to treat bipolar disorder, is an effective means to slow inclusion body myositis, or IBM, which affects the elderly.

Scientists Frank LaFerla and Masashi Kitazawa used mice, which were genetically engineered to have IBM, to test the drug and received positive results. Within six months motor function increased through daily use of the drug, according to the study.

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The muscles in the mice treated also had decreased levels of protein that could be related to muscle inflammation associated with IBM, scientists said.

— Daniel Tedford


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