The Anteaters (11-2, 6-2 in conference) outdid the Cougars (9-1, 5-1) in hitting, blocking, serving and passing to earn their first win in Provo since 1991.
UCI hit .312 as a team, 23 points better than BYU, and ahead of the Cougars, 17 1/2 -14 in team blocks.
The 17 1/2 blocks were a season high for the 'Eaters.
Senior Jayson Jablonsky, the 2006 National and MPSF Player of the Year, who hit .000 Friday, led the winners with 21 kills (hitting .381), and 10 digs. He also had two of UCI's five aces and added two block assists.
Senior All-American Matt Webber, who also hit .000 Friday, produced 14 kills and hit .393 to go with two aces and six block assists.
Senior middle blocker David Smith had 10 kills, hit .562, and led the team with 10 block assists, while junior middle Aaron Harrell added 13 kills and three block assists.
"I think this win shows how we can turn it around after being crushed last night," Jablonsky said. "After [Friday] everybody got together and we talked about wanting to come out and have some fun and just play Irvine volleyball."
UCI Coach John Speraw said Jablonsky and Webber came to the party Saturday, helping push the Anteaters over the top.
"We had some guys who hadn't played well the last couple weeks who came back and played well tonight," said Speraw, who ranked the victory near the top during his five-seasons at the UCI helm. "Specifically, both Jablonsky and Webber had great nights tonight."
Harrell, who when not on the court was yelling constant encouragement to his teammates between serves, said it was an emotional victory.